Arctic root

Common name

Arctic root

ID

HD0071

Scientific name of the plant

Rhodiola rosea L.

Anatomical part for use

root

Human use

Fatigue & weakness,Mental stress & mood disorders

Summary

Rhodiola rosea (commonly golden root, rose root, roseroot, Aaron's rod, Arctic root, king's crown, lignum rhodium, orpin rose) is a perennial flowering plant in the family Crassulaceae. It grows naturally in wild Arctic regions of Europe (including Britain), Asia, and North America ( N.B., Nfld. and Labrador, N.S., QC.; Alaska, Maine, N.Y., N.C., Pa., Vt), and can be propagated as a groundcover. Rhodiola rosea has been used in traditional medicine for several disorders, notably including treatment of anxiety and depression. As of 2019, there is no high-quality randomized or clinical controlled trails adequately assessing its effectiveness for treating "physical fatigue and mild to moderate depression and/or mental fatigue", for "enhancing physical endurance and performance" or "evaluating [its] adaptogenic properties". The United States Food and Drug Administration has issued several warnings to manufacturers of R. rosea dietary supplements for making false health claims about its safety and efficacy.The plant's status is threatened in many countries due to rapidly growing demand. Supply comes mostly from wild harvesting on an industrial scale, and a combination of growing scarcity and a lack of regulation has led to environmental degradation, substitution/adulteration in the market, and illegal harvesting in protected areas.

Evidence Level

Level 0 (No convinced report of liver injury caused by herbal and dietary supplement)

Hepatotoxicity Description

N/A

Traditional medicine

In Russia and Scandinavia, R. rosea has been used for centuries to cope with the cold Siberian climate and stressful life. It is also used to increase physical endurance and resistance to high-altitude sickness, but the scientific evidence for such benefits is weak. The plant has been used in traditional Chinese medicine, where it is called hóng jǐng tiān. A 2012 report by the European Medicines Agency on literature concerning the dried extract of R. rosea stated that "The published clinical trials exhibit considerable deficiencies in their quality. Therefore 'well-established use' cannot be accepted" and added: "The traditional use as an adaptogen 'for temporary relief of symptoms of stress such as fatigue and sensation of weakness' is appropriate for traditional herbal medicinal products. ... The long-standing use as well as the outcome of the clinical trials support the plausibility of the use of the mentioned herbal preparation in the proposed indication." (Source: Wiki)

Relevant Public Information

Wiki
EMA
Nature Medicines